“Achieving lasting remission from HIV. HP plans to save millions by laying off thousands, ramping up AI use.”
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Accessed on 29 November 2025, 2053 UTC.
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Russ Roberts (https://hawaiisciencejournal.com).
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Around the world, some 40 million people are living with HIV. And though progress in treatment means the infection isn’t the death sentence it once was, researchers have never been able to bring about a cure. Instead, HIV-positive people must take a cocktail of antiretroviral drugs for the rest of their lives. But in 2025, researchers reported a breakthrough that suggests that a “functional” cure
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HP Inc. said that it will lay off 4,000 to 6,000 employees in favor of AI deployments, claiming it will help save $1 billion in annualized gross run rate by the end of its fiscal 2028. HP expects to complete the layoffs by the end of that fiscal year. The reductions will largely hit product development, internal operations, and customer support, HP CEO Enrique Lores said during an earnings call o
A Soyuz rocket launched on Thursday carrying Roscosmos cosmonauts Sergei Kud-Sverchkov and Sergei Mikayev, as well as NASA astronaut Christopher Williams, for an eight-month mission to the International Space Station. The trio of astronauts arrived at the orbiting laboratory without incident. However, on the ground, there was a serious problem during the launch with the ground systems that suppor
Yesterday
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Earlier in 2025 we celebrated Prime Day—the yearly veneration of the greatest Transformer of all, Optimus Prime (in fact, Optimus Prime is so revered that we often celebrate Prime Day twice!). But in the fall, as the evenings lengthen and the air turns chill, we pause to remember a much more somber occasion: Black Friday, the day Optimus Prime was cruelly cut down by the treacherous hand of his a
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When the US Fish and Wildlife Service reintroduced 14 gray wolves to Yellowstone National Park in 1995, the animals were, in some ways, stepping into a new world. After humans hunted wolves to near-extinction across the Western US in the early 20th century, the carnivore’s absence likely altered ecosystems and food webs across the Rocky Mountains. Once wolves were reintroduced to the landscape, s
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We recently looked at Tiny vinyl , a new miniature vinyl single format developed through a collaboration between a toy industry veteran and the world’s largest vinyl record manufacturer. The 4-inch singles are pressed in a process nearly identical to standard 12-inch LPs or 7-inch singles, except everything is smaller. They have a standard-size spindle hole and play at 33⅓ RPM, and they hold up t
Nov 27, 2025
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Peruse a list of films released in 1985 and you’ll notice a surprisingly high number of movies that have become classics in the ensuing 40 years. Sure, there were blockbusters like Back to the Future, The Goonies, Pale Rider, The Breakfast Club and Mad Max: Beyond Thunderdome , but there were also critical arthouse favorites like Kiss of the Spider Woman and Akira Kurosawa’s masterpiece, Ran . Si
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If you need some motivation to keep from eating too much this Thanksgiving, here it is: Doctors in Romania pulled an 11 cm (4.3 inch) living, writhing round worm from a woman’s left eyelid. According to a report in the New England Journal of Medicine , the worm likely hatched from a hard lump in her right temple, which the woman recalled first spotting a month beforehand. She also noticed that th
Nov 26, 2025
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Around this time last year, officials at United Launch Alliance projected 2025 would be their busiest year ever. Tory Bruno, ULA’s chief executive, told reporters the company would launch as many as 20 missions this year, with roughly an even split between the legacy Atlas V launcher and its replacement — the Vulcan rocket. Now, it’s likely that ULA will close out 2025 with six flights —five with
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Worries about the US grid’s ability to handle the surge in demand due to data center growth have made headlines repeatedly over the course of 2025. And, early in the year, demand for electricity had surged by nearly 5 percent compared to the year prior, suggesting the grid might truly be facing a data center apocalypse. And that rise in demand had a very unfortunate effect: Coal use rose for the
Under ardent anti-vaccine Health Secretary Robert F. Kennedy Jr., the Centers for Disease Control and Prevention has named Louisiana Surgeon General Ralph Abraham as its new principal deputy director—a choice that was immediately called “dangerous” and “irresponsible,” yet not as bad as it could have been, by experts. Physician Jeremy Faust revealed the appointment in his newsletter Inside Medici
Facing five lawsuits alleging wrongful deaths, OpenAI lobbed its first defense Tuesday, denying in a court filing that ChatGPT caused a teen’s suicide and instead arguing the teen violated terms that prohibit discussing suicide or self-harm with the chatbot. The earliest look at OpenAI’s strategy to overcome the string of lawsuits came in a case where parents of 16-year-old Adam Raine accused Ope
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After nearly a decade of development, Russia’s newest launch vehicle is close to its debut flight. The medium-lift Soyuz 5 rocket is expected to launch from the Baikonur Cosmodrome before the end of the year. The Russian space corporation, Roscosmos, has released images of final processing of the Soyuz 5 rocket at the Progress Rocket and Space Center in Samara, Russia, earlier this month before t
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With the recent releases of visionOS 26 and newly refreshed Vision Pro hardware, it’s an ideal time to check in on Apple’s Vision Pro headset—a device I was simultaneously amazed and disappointed by when it launched in early 2024. I still like the Vision Pro, but I can tell it’s hanging on by a thread. Content is light, developer support is tepid, and while Apple has taken action to improve both,
Crypto-hoarding companies are ditching their holdings in a bid to prop up their sinking share prices, as the craze for “digital asset treasury” businesses unravels in the face of a $1 trillion cryptocurrency rout. Shares in Michael Saylor-led Strategy, the world’s biggest corporate bitcoin holder, have tumbled 50 percent over the past three months, dragging down scores of copycat companies. About
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When four people were arrested and charged with a conspiracy to illegally export Nvidia chips to China, there was an interesting side note. One of the arrestees, Alabama resident Brian Raymond, was the chief technology officer of an AI company called Corvex. Or was he? Corvex certainly seemed to think that Raymond was its CTO in the days before his indictment. Corvex named Raymond as its CTO in a
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Many dog breeds are noted for their personalities and behavioral traits, from the distinctive vocalizations of huskies to the herding of border collies. People have worked to identify the genes associated with many of these behaviors, taking advantage of the fact that dogs can interbreed. But that creates its own experimental challenges, as it can be difficult to separate some behaviors from phys
Nov 25, 2025
The popularity of GLP-1 weight-loss medications continues to soar—and their uptake is helping to push down obesity rates on a national scale—but a safe, evidence-based way off the drugs isn’t yet in clear view. An analysis published this week in JAMA Internal Medicine found that most participants in a clinical trial who were assigned to stop taking tirzepatide (Zepbound from Eli Lilly) not only r
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Plex is starting to enforce its new rules, which prevent users from remotely accessing a personal media server without a subscription fee. Previously, people outside of a server owner’s network could access the owner’s media library through Plex for free. Under the new rules announced in March , a server owner needs to have a Plex Pass subscription, which starts at $7 per month, to grant users re
It’s not a bad time to upgrade your gaming PC. Graphics card prices in the 2020s have undulated continuously as the industry has dealt with pandemic and AI-related shortages, but it’s actually possible to get respectable mainstream- to high-end GPUs like AMD’s Radeon RX 9060 XT and 9070 series or Nvidia’s RTX 5060 , 5070 , and 5080 series for at or slightly under their suggested retail prices rig
An unpiloted Chinese spacecraft launched late Monday and linked up with the country’s Tiangong space station a few hours later, providing a lifeboat for three astronauts stuck in orbit without a safe ride home. A Long March 2F rocket fired its engines and lifted off with the Shenzhou 22 spacecraft, carrying cargo instead of a crew, at 11:11 pm EST Monday (04:11 UTC Tuesday). The spacecraft docked
RealPage has agreed to settle an antitrust lawsuit raised by the Department of Justice, alleging that landlords used its tools to coordinate efforts to artificially raise rental prices across the US. In a press release , the DOJ promised the proposed settlement “would help restore free market competition in rental markets for millions of American renters.” For years since the pandemic started, re
After Valve announced its upcoming Steam Machine living room box earlier this month, some analysts suggested to Ars that Valve could and should aggressively subsidize that hardware with “loss leader” pricing that leads to more revenue from improved Steam software sales. In a new interview with YouTube channel Skill Up , though, Valve’s Pierre-Loup Griffais ruled out that kind of console-style pri
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Our exploration of the outer Solar System has revealed a host of icy moons, many with surface features that suggest a complex geology. In some cases, these features—most notably the geysers of Enceladus—hint at the presence of oceans beneath the icy surfaces. These oceans have been ascribed to gravitational interactions that cause flexing and friction within the moon, creating enough heat to melt
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Like many mushroom harvesters, I got interested in foraging for fungi during the COVID-19 pandemic. I had been preparing for a summer of field work studying foraged desert plants in a remote part of Australia when the pandemic hit, and my travel plans were abruptly frozen. It was March, right before morel mushrooms emerge in central Pennsylvania. I wasn’t doing a lot other than going on long hike
Nov 24, 2025
Anthropic today released Opus 4.5 , its flagship frontier model, and it brings improvements in coding performance, as well as some user experience improvements that make it more generally competitive with OpenAI’s latest frontier models. Perhaps the most prominent change for most users is that in the consumer app experiences (web, mobile, and desktop), Claude will be less prone to abruptly hard-s
The commander of the military unit responsible for running the Cape Canaveral spaceport in Florida expects SpaceX to begin launching Starship rockets there next year. Launch companies with facilities near SpaceX’s Starship pads are not pleased. SpaceX’s two chief rivals, Blue Origin and United Launch Alliance, complained last year that SpaceX’s proposal of launching as many as 120 Starships per y
After Donald Trump curiously started referring to the Department of Government Efficiency exclusively in the past tense, an official finally confirmed Sunday that DOGE “doesn’t exist.” Talking to Reuters , Office of Personnel Management (OPM) Director Scott Kupor confirmed that DOGE—a government agency notoriously created by Elon Musk to rapidly and dramatically slash government agencies—was term
Some members of the maker community are distraught about Arduino’s new terms of service (ToS), saying that the added rules put the company’s open source DNA at risk. Arduino updated its ToS and privacy policy this month, which is about a month after Qualcomm announced that it’s acquiring the open source hardware and software company. Among the most controversial changes is this addition: User sha
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The emergence of synthetic pigments in the 19th century had an immense impact on the art world, particularly the availability of emerald-green pigments, prized for their intense brilliance by such masters as Paul Cézanne, Edvard Munch, Vincent van Gogh, and Claude Monet. The downside was that these pigments often degraded over time, resulting in cracks and uneven surfaces and the formation of dar
The US space agency ended months of speculation about the next flight of Boeing’s Starliner spacecraft, confirming Monday that the vehicle will carry only cargo to the International Space Station. NASA and Boeing are now targeting no earlier than April 2026 to fly the uncrewed Starliner-1 mission, the space agency said. Launching by next April will require completion of rigorous test, certificati
AT&T provided flights from Washington, DC, to Las Vegas and accommodation so Ars could attend the Las Vegas Grand Prix. Ars does not accept paid editorial content. LAS VEGAS—Formula 1 held the third annual Las Vegas Grand Prix this past weekend in the Nevada city. The race is an outlier in so many ways, and a divisive one at that. Some love the bright lights that make it appear to be set in Mega-
The UK government will promise to buy emerging chip technology from British companies in a 100 million pound ($130 million) bid to boost growth by supporting the artificial intelligence sector. Liz Kendall, the science secretary, said the government would offer guaranteed payments to British startups producing AI hardware that can help sectors such as life sciences and financial services. Under a
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The company that pioneered small launch has had a big year. Rocket Lab broke its annual launch record with the Electron booster—17 successful missions this year, and counting—and is close to bringing its much larger Neutron rocket to the launch pad. The company also expanded its in-space business, including playing a key role in supporting the landing of Firefly’s Blue Ghost mission on the Moon a
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In 2016, the legendary Japanese filmmaker Hayao Miyazaki was shown a bizarre AI-generated video of a misshapen human body crawling across a floor. Miyazaki declared himself “utterly disgusted” by the technology demo, which he considered an “insult to life itself.”
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