“7 basic science discoveries that changed the world.”
Views expressed in this science and technology update are those of the reporters and correspondents.
Accessed on 30 October 2025, 1459 UTC.
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Russ Roberts (https://hawaiisciencejournal.com).
Most popular
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03474-x Ozempic, MRI machines and flat screen televisions all emerged out of fundamental research decades earlier — the very types of study being slashed by the US government.
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Nature, Published online: 30 October 2025; doi:10.1038/d41586-025-03499-2 The month’s sharpest science shots, selected by Nature’s photo team.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03290-3 Politics trumps salary as the main reason academics are looking for jobs in other states, a survey of university educators shows.
Yesterday
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03539-x An artificial-intelligence tool is helping to crack the challenge of forecasting hurricane intensity.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09629-0 Reply to: On anisotropy in cubic Cu 2 O photoelectrodes
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09628-1 On anisotropy in cubic Cu 2 O photoelectrodes
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09380-6
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03541-3 Researchers immunized an alpaca and a llama with snake venoms, and combined some of the antibodies produced into a potent cocktail.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03551-1 Cold-induced RNA-binding protein was shown to enhance DNA repair — plus, a more universal snakebite venom.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09381-5
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09693-6 A majority methylammonium and iodine edge termination is observed by electron ptychography in the perovskite methylammonium lead iodide, and the stability of its edges and internal defects depends on the concentration and type of vacancies present.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09661-0 A recombinant antivenom composed of eight nanobodies provides broad protection against venom-induced lethality and dermonecrosis in mice challenged with venoms from cobras, mambas and rinkhals snakes.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09675-8 A ductile inorganic-rich solid–electrolyte interphase that retains its structural integrity and allows easy ion diffusion enables a long cycle life under practical conditions for lithium metal batteries.
Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09694-5 Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09647-y Thiorphan is identified as a new and effective drug treatment for spinal cord injury that can be adopted across nervous system disease states in the development of new therapies for human neurological disorders.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09630-7 Experimental evidence shows that hydrogen–silicate reactions can generate abundant water in sub-Neptunes, suggesting hydrogen-rich planets have the potential to reach water-rich compositions.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09659-8 Experimental evidence of coherent charge transport in the normal state of the kagome metal CsV3Sb5 is presented, revealing the nature of correlated order in kagome metals and new directions for exploring quantum coherence in correlated electron systems.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09678-5 A catalogue of nucleotide-binding leucine-rich repeat (NLR) genes in wild and cultivated potato genomes enables the identification of genes that confer protection against late blight, and provides a transgene-free strategy for engineering disease resistance in potato.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09657-w The viability of Antarctic ice shelves under low rates and high rates of global warming is modelled to estimate when it will become unfeasible for the ice shelves to maintain their present-day shape.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09688-3 Structural studies of 16 native yeast ribosomal small subunit processome structures provide insights into the mechanisms governing the transformation into a pre-40S particle.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09676-7 A pangenome of oat, assembled from 33 wild and domesticated oat lines, sheds light on the evolution and genetic diversity of this cereal crop and will aid genomics-assisted breeding to improve productivity and sustainability.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09695-4 Ion-channel conductance levels are controlled by the bending patterns of pore-forming transmembrane helices in the heterotetrameric neuronal channel GluN1a-2B N-methyl-D-aspartate receptor.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09650-3 A soft artificial muscle with programmable actuation is achieved using microbubble arrays and targeted ultrasound activation, with potential applications in soft robotics, wearable technologies, haptics and biomedical instrumentation.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09690-9 Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the efficiency of movement responses.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09686-5 This multi-omic longitudinal analysis of the healthy human peripheral immune system constructs the Human Immune Health Atlas and assembles data on immune cell composition and state changes with age, including responses to cytomegalovirus infection and influenza vaccination.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09660-1 An ecosystem energetics approach, quantifying trophic energy flows across species, offers a unified framework for linking animal biodiversity loss to changes in ecosystem function and Earth system processes.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09689-2 The low-density lipoprotein receptor family members LRP1, LRP4 and VLDLR are entry receptors for yellow fever virus.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09625-4 Magnetotelluric data provide evidence of a large melt-rich magmatic reservoir beneath Mayotte island that might be connected to the system that fed the large submarine eruption of Fani Maoré in 2018–2019.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09658-9 A model has been developed to identify the least-cost technology pathway for global individual iron and steel plants over 2020–2050 in alignment with national carbon-neutrality targets.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09632-5 Coupling live-cell imaging, machine learning and genomic sequencing, the MAGIC platform enables investigation of the cellular context, mutation rates and triggers of spontaneous chromosomal abnormality formation, shedding light on fundamental determinants of chromosomal instability.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09699-0 Embedding non-porous MXene film into metal thin films can achieve unprecedented shielding performance, which can be used to protect electronic components and equipment from electromagnetic noise.
Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03213-2 Soft materials filled with microbubbles flex when exposed to ultrasound — forming the basis of wireless devices that can be made to pass through organs such as the intestine.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03404-x Pollution from wildfire smoke is increasing in the United States. Climate change is projected to exacerbate the problem, leading to 70,000 premature deaths each year by 2050. If no extra measures are taken, wildfire smoke could become one of the country’s worst climate disasters.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03461-2 Compounds that bind to the intracellular core of G-protein-coupled receptors can encourage interactions with some G proteins and prevent them with others, leading to a switch in downstream signalling pathways. Rational design of such core-targeted compounds could be used to find small molecules that modulate this diverse su
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03216-z Improved therapies to treat snakebite are needed. A new approach might lead to the development of more-effective treatments for use in the clinic.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03214-1 A reaction between hydrogen and magma at high pressure can produce water, which might explain evidence for ‘wet planets’ in places where water can’t condense.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03462-1 Shrinking conventional visual displays for use closer to the eye causes problems with colour mixing and requires a trade-off between resolution and brightness. An innovative technology called retina E-paper brings ultrahigh resolution to reflective displays, reaching the limits of human vision when scaled to pupil-sized scr
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03511-9 A cold-activated protein that mends damaged DNA could play a part in keeping the bowhead whale in tip-top shape.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03215-0 As the giants of the animal kingdom dwindle in numbers, a new way to assess ecosystem function sheds light on animals’ changing ecological contributions.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03538-y Flexible device inspired by an elephant’s trunk can deliver healing hydrogels after surgery.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03357-1 In the rush to adopt autonomous systems, countries risk overlooking crucial safeguards, warns international law professor Nehal Bhuta.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03385-x A weapons specialist answers Nature’s questions on the future of technology and conflict.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03480-z The near-invisible robots have yet to make it to a clinical trial, but scientists are already using them as a way to diagnose and treat various cancers.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03261-8 A search for meaning.
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03471-0 A fresh set of benchmarks could help specialists to better understand artificial intelligence.
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Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09719-z
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Nature, Published online: 29 October 2025; doi:10.1038/d41586-025-03470-1 In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.
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Nature, Published online: 28 October 2025; doi:10.1038/d41586-025-03548-w Scientists are only now starting to understand the full role of the plant cell wall. Plus, the risks of a less-familiar form of avian influenza virus and how tides impact the development of urbanization.
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Nature, Published online: 27 October 2025; doi:10.1038/d41586-025-03545-z ‘No one epidemic’ ravaged Napoleon’s troops on their retreat from Moscow, researchers say. Plus, large language models
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