“LIGO is 10 years old: Black Hole breakthroughs will ‘only get better.'”
Views expressed in this science and technology update are those of the reporters and correspondents. Accessed on 12 September 2025, 1414 UTC.
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Russ Roberts (https://hawaiisciencejournal.com).
Today
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Nature, Published online: 12 September 2025; doi:10.1038/d41586-025-02941-9 A decade after the pair of observatories first detected gravitational waves, researchers are drawing up ambitious plans for its successors.
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Nature, Published online: 12 September 2025; doi:10.1038/d41586-025-02777-3 A difficult thing to fix.
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Nature, Published online: 11 September 2025; doi:10.1038/d41586-025-02982-0 Carbon emissions from individual energy giants can be directly linked to one quarter of heatwaves between 2000 and 2023. Plus, a brain ‘dial’ that turns the desire to eat on and off in mice and the researchers fighting back against the Trump administration’s assault on US science.
Yesterday
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Nature, Published online: 12 September 2025; doi:10.1038/d41586-025-02520-y YATSI aims to represent scientists based in academia and in industry, and to build bridges between the two sectors.
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Nature, Published online: 11 September 2025; doi:10.1038/d41586-025-02942-8 A report by the panel downplays the ills of global warming and was key to White House efforts to revoke federal authority to regulate climate.
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Nature, Published online: 11 September 2025; doi:10.1038/d41586-025-02946-4 The age-old philosophical question of whether we seecolours the same way has been explored with brain scans.
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Nature, Published online: 11 September 2025; doi:10.1038/d41586-025-02936-6 Authors and peer reviewers are failing to disclose the use of LLMs despite journal policies limiting their use.
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Nature, Published online: 11 September 2025; doi:10.1038/s41586-025-09597-5
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Nature, Published online: 11 September 2025; doi:10.1038/d41586-025-02904-0 Laser method could help to pinpoint the age of many fossils, but some palaeontologists say further research is needed to verify the technique.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02943-7 Farms across Europe are turning to regenerative agriculture to save their crops from the effects of climate change. Plus, a prototype ‘helmet’ for delivering non-invasive brain treatments and a vaccine against chlamydia for koalas.
Sep 10, 2025
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Nature, Published online: 11 September 2025; doi:10.1038/d41586-025-02889-w Julie Gould explores some of the theories and frameworks to help identify future work goals and achieve them.
Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02905-z A report finds that death rates from cancer and heart disease have declined since 2010 in roughly 150 countries.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02895-y Nature talks to researchers about why they moved and how they relocated successfully.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02875-2 Lightweight, battery-powered shirt could maintain skin at a comfortable temperature for hours.
Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02915-x Nearly one-quarter of heatwaves would have been ‘virtually impossible’ without global warming — and can be attributed to the emissions of individual energy producers.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09590-y
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02938-4 Attribution study suggests major energy producers play an outsized role in causing extreme heatwaves — plus, the scientists fighting back against US funding cuts.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09482-1 A modelling study based on satellite observations, machine learning and a chemical transport model quantifies the global and regional exposure to particulate-matter pollution and the human health impacts related to the 2023 Canadian wildfires.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09496-9 A rhynchocephalian skeleton around 3–7 million years older than the oldest currently known lepidosaur fossil provides important insight into the origin of lizards and snakes.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09508-8 Neural tissue is a key signalling centre for fundic–antral patterning in development of gastric organoids featuring asymmetric PDX1 patterning.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09494-x The results from a state-of-the-art suite of hydrodynamical cosmological zoom-in simulations show how globular clusters naturally emerge in the Standard Cosmology and also reveal the existence of a new class of object called globular-cluster-like dwarfs.
Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09499-6 Establishing antisense oligomers as versatile, non-genetic tools to silence phage mRNAs opens applications in basic research and biotechnology, as shown by identifying essential factors for propagation of the nucleus-forming jumbo phage ΦKZ such as the RNase H-like protein ΦKZ155.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09506-w Amino acids possess a new and broad colloidal property: they stabilize patchy nanoscale colloids, such as proteins, by adsorbing onto their surfaces through weak interactions.
Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09374-4 Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09513-x PLD4 loss-of-function mutations in patients with systemic lupus erythematosus leads to excessive activation of TLR7 and TLR9.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09518-6 Red light- or ultrasound-controlled proximity labelling is engineered to stimulate clustering-induced receptor activation and downstream signalling amplification to promote antitumour immune responses.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09520-y Loss-of-function variants of ABCA7, associated with Alzheimer’s disease, result in disrupted lipid metabolism, mitochondrial function, DNA repair and synaptic signalling pathways in the human brain.
Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09492-z Glutamatergic and GABAergic (γ-aminobutyric acid-producing) cortical neuronal activity drives proliferation of small lung cell cancer via paracrine interactions and through synapses formed with tumour cells.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09483-0 Analysis of samples from the asteroid Ryugu provide evidence of late fluid flow in a carbonaceous asteroid, indicating that such bodies may have retained two to three times more water than previously thought.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09502-0 Unbiased clustering analysis of the skeletal muscle RNAome in patients with cancer identifies two molecular subtypes, one of which distinguishes individuals with cachexia and indicates potential target pathways for future research.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09488-9 Resonant inelastic X-ray scattering can be used to measure the spin current carried by magnons in the presence of temperature gradients across a magnetic insulator.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09514-w Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.
Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09450-9 Climate change made 213 historical heatwaves reported over 2000–2023 more likely and more intense, to which each of the 180 carbon majors (fossil fuel and cement producers) substantially contributed.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09413-0 A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and organic signatures that warrant consideration as potential biosignatures.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09493-y An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and developing more effective myeloid-targeting therapies.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09498-7 Using 19F nuclear magnetic resonance to study LiF–LiH solid solutions revealed that it is present in the solid–electrolyte interphase of lithium metal batteries and confirms the heterogeneous nature of LiF in such interphases.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09434-9 Small cell lung cancer cells form functional synapses with glutamatergic neurons, receiving synaptic transmissions and deriving a proliferative advantage from these interactions.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09491-0 Cryogenic electron microscopy structures and functional analyses reveal that NCLX functions as a H+/Ca2+ rather than a Na+/Ca2+ exchanger, and uncover its transport mechanism with implications for therapies treating cardiac and neurodegenerative disorders related to abnormal mitochondrial Ca2+.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09456-3 A superconducting quantum computer is used to realize an out-of-equilibrium topologically ordered state, which hosts anyonic excitations.
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Nature, Published online: 10 September 2025; doi:10.1038/s41586-025-09475-0 Digital quantum simulations of Kitaev’s honeycomb model are realized for two-dimensional fermionic systems using a reconfigurable atom-array processor and used to study the Fermi–Hubbard model on a square lattice.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02861-8 A bacterium that uses sulfide as an energy source to metabolize solid iron oxides has been discovered, revealing a biological reaction that was previously assumed to be solely chemical. This finding uncovers a firm microbial link between sulfur and iron cycling in oxygen-free environments such as aquatic sediments.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02869-0 Artificially generated data can help to train AI models when real data are scant, but more focus is needed on validating the results.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02911-1 Representatives of four medical research centres have told Nature they have waived normal ethical review because ‘synthetic’ data do not contain real or traceable patient information.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02598-4 A computational model of the early-to-present-day Universe predicts that some of the first stars formed in structures that challenge conventional classification.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02864-5 Atoms are the fundamental building blocks of metallic materials, and their arrangement and distribution determine the material’s properties. Rearranging atoms from a random, disordered state into a carefully ordered dual-scale pattern enhances the mechanical performance of alloys under extremely cold conditions.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02256-9 An innovative method to trace tumour evolution using patterns of fluctuating DNA modifications could be implemented in the clinic to predict cancer progression.
Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02871-6 Master-control area integrates information about hunger, a food’s tastiness and more — and can even drive intake of plastic pellets.
Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02596-6 The emissions of leading fossil-fuel and cement producers have been systematically linked to particular heatwaves. Three scientists discuss the methodology behind the result and its potential impact on climate-liability court cases.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02858-3 In an intricate interaction spanning domains of life, the bacterium Salmonella hijacks the yeast Candida to make it produce and release the amino acid arginine in the gut. Arginine increases the virulence of Salmonella and downregulates the host’s immune response to Salmonella infection, leading to more-severe disease.
Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02872-5 Discovery joins a list of the greatest hits of the LIGO detector, which ten years ago became the first to detect gravitational waves.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02868-1 The US administration is attempting to undermine efforts to curb greenhouse-gas emissions. It will ultimately leave that country, and the world, worse off.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02597-5 The Perseverance rover on Mars has observed unusual minerals associated with organic matter — raising questions about the geochemistry of ancient Mars.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02775-5 Welcome to the garden.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02813-2 From large national databases to bespoke sample collections, biobanks offer a wealth of avenues for scientific enquiry.
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Nature, Published online: 10 September 2025; doi:10.1038/d41586-025-02811-4 Through lawsuits, grant tracking, whistle-blowing and more, resistance to the US war on science is growing.
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Nature, Published online: 09 September 2025; doi:10.1038/d41586-025-02935-7 Scans suggest that colours light up the same parts of different people’s brains. Plus, a pig-organ transplant success story and how warming water could decimate a vital phytoplankton.
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